hrp0084p1-26 | Diabetes | ESPE2015

Human Placenta-Derived Mesenchymal Stem Cells: A Novel Protocol for Pancreatic Differentiation

Patianna Viviana Dora , Okere Bernard , Predieri Barbara , Bruzzi Patrizia , Iughetti Lorenzo

Background: Placenta tissue hold great promise as a source of cells for regenerative medicine due to its plasticity and easy availability. Amniotic Mesenchymal Stem Cells (AMSC) represent a potentially unlimited source of functional pancreatic endocrine lineage cells, used to replenish the islet mass in diabetic patients.Objective and hypotheses: The aim of our study is to culture AMSC in serum-free condition preserving their phenotypic traits. These cul...